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Brinton Seashore-Ludlow

Brinton Seashore-Ludlow

Senior Forskningsspecialist | Docent
Telefon: +46852487873
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: Tomtebodavägen 23B, SciLifeLab, 17165 Stockholm
Postadress: K7 Onkologi-Patologi, K7 Forskning Kallioniemi SeashoreLudlow, 171 77 Stockholm
Del av:

Om mig

  • I currently hold two positions at the Karolinska Institute (KI). I am a team
    leader in the larger group of Olli Kallioniemi, and group leader of the
    biology team at Chemical Biology Consortium Sweden [1] (CBCS), a national
    infrastructure at SciLifeLab [2].
    2013-2015: *PostDoc*; Broad Institute of Harvard and MIT
    2007-2012 *PhD*; KTH Royal Institute of Technology, Stockholm, Sweden
    2005-2007 *MSc*; California Institute of Technology, Pasadena, CA, USA
    2001-2005 *BA*; Macalester College, St. Paul, MN, USA
    [1]
    [2]

Forskningsbeskrivning

  • .... Our ultimate goal is to promote the move away from one-size-fits-all
    therapies to improve patient outcome through treatment stratification
    and tailoring. Despite advances in precision medicine diagnostics, there
    are still major opportunities to improve individualized patient care
    throughout the entire health care value chain, spanning from preclinical
    studies in drug discovery through to the design of precision
    diagnostics. Research in my team focuses on challenges central to these
    fields, developing technologies and disease models that enable direct
    measurement of patient response to treatment ex vivo and investigation
    of the molecular determinants of drug response. Such methods and model
    systems are critical to improve the study of disease biology, identify
    and validate new drug targets, correctly prioritize drug candidates for
    clinical trials, uncover potential biomarkers for future patient
    stratification and have even recently been used successfully as
    diagnostics to match patients to effective treatments.
    .... Our translational research group and surrounding team of clinicians and
    experts has two major themes as described below united by the main goal
    of investigating drug response and biomarkers in primary patient cells
    and other near-patient models of disease.

Undervisning

  • I co-organize the Overview Course in Cancer Drug Discovery. [1]
    [1] ;jsessionid=e5e6391eaf4fb87efa1707889446

Artiklar

  • Article: COMMUNICATIONS BIOLOGY. 2025;8(1):303
    Sharma O; Gudoityte G; Minozada R; Kallioniemi OP; Turkki R; Paavolainen L; Seashore-Ludlow B
  • Article: ISCIENCE. 2025;28(2):111864
    Pan Y; Berkovska O; Marathe S; Mermelekas G; Gudoityte G; Wolide AD; Arslan T; Seashore-Ludlow B; Lehtio J; Orre LM
  • Article: ADVANCED SCIENCE. 2025;12(3):e2407572
    Youhanna S; Kemas AM; Wright SC; Zhong Y; Klumpp B; Klein K; Motso A; Michel M; Ziegler N; Shang M; Sabatier P; Kannt A; Sheng H; Oliva-Vilarnau N; Buettner FA; Seashore-Ludlow B; Schreiner J; Windbergs M; Cornillet M; Bjorkstrom NK; Hulsmeier AJ; Hornemann T; Olsen JV; Wang Y; Gramignoli R; Sundstrom M; Lauschke VM
  • Article: CANCER LETTERS. 2024;605:217261
    Pepich A; Tummler C; Abu Ajamieh S; Treis D; Boje AS; Vellema Q; Tsea I; Akerlund E; Seashore-Ludlow B; Fard SS; Kogner P; Johnsen JI; Wickstrom M
  • Article: CELL DEATH & DISEASE. 2024;15(9):694
    Murga M; Lopez-Pernas G; Soliva R; Fueyo-Marcos E; Amor C; Faustino I; Serna M; Serrano AG; Diaz L; Martinez S; Blanco-Aparicio C; Anton ME; Seashore-Ludlow B; Pastor J; Jafari R; Lafarga M; Llorca O; Orozco M; Fernandez-Capetillo O
  • Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2024;43(1):107
    Fonseca P; Cui W; Struyf N; Tong L; Chaurasiya A; Casagrande F; Zhao H; Fernando D; Chen X; Tobin NP; Seashore-Ludlow B; Lundqvist A; Hartman J; Gondor A; Ostling P; Holmgren L
  • Article: ONCOGENE. 2024;43(15):1113-1126
    Reid SE; Pantaleo J; Bolivar P; Bocci M; Sjolund J; Morsing M; Cordero E; Larsson S; Malmberg M; Seashore-Ludlow B; Pietras K
  • Article: NPJ PRECISION ONCOLOGY. 2024;8(1):38
    Struyf N; Osterroos A; Vesterlund M; Arnroth C; James T; Sunandar S; Mermelekas G; Bohlin A; Hamberg Levedahl K; Bengtzen S; Jafari R; Orre LM; Lehtio J; Lehmann S; Ostling P; Kallioniemi O; Seashore-Ludlow B; Erkers T
  • Article: SCIENTIFIC REPORTS. 2024;14(1):4000
    Bwanika HC; Leo IR; Struyf N; Talanti A; Aswad L; Konnur A; Bjoerklund A-C; Heyman M; Rassidakis G; Erkers T; Seashore-Ludlow B; Jafari R; Pokrovskaja Tamm K
  • Article: MOLECULAR ONCOLOGY. 2024;18(2):317-335
    Zaghmi A; Aybay E; Jiang L; Shang M; Steinmetz-Spah J; Wermeling F; Kogner P; Korotkova M; Ostling P; Jakobsson P-J; Seashore-Ludlow B; Larsson K
  • Article: SLAS TECHNOLOGY. 2023;28(6):423-432
    Trossbach M; Akerlund E; Langer K; Seashore-Ludlow B; Joensson HN
  • Article: NPJ PRECISION ONCOLOGY. 2023;7(1):111
    Akerlund E; Gudoityte G; Moussaud-Lamodiere E; Lind O; Bwanika HC; Lehti K; Salehi S; Carlson J; Wallin E; Fernebro J; Ostling P; Kallioniemi O; Joneborg U; Seashore-Ludlow B
  • Article: NUCLEIC ACIDS RESEARCH. 2023;51(W1):W57-W61
    Potdar S; Ianevski F; Ianevski A; Tanoli Z; Wennerberg K; Seashore-Ludlow B; Kallioniemi O; Ostling P; Aittokallio T; Saarela J
  • Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(6):925-940
    Jadersten M; Lilienthal I; Tsesmetzis N; Lourda M; Bengtzen S; Bohlin A; Arnroth C; Erkers T; Seashore-Ludlow B; Giraud G; Barkhordar GS; Tao S; Fogelstrand L; Saft L; Ostling P; Schinazi RF; Kim B; Schaller T; Juliusson G; Deneberg S; Lehmann S; Rassidakis GZ; Hoglund M; Henter J-I; Herold N
  • Article: MICROMACHINES. 2022;13(11):1823
    Trossbach M; Sanz MDL; Seashore-Ludlow B; Joensson HN
  • Article: CELL DEATH & DISEASE. 2022;13(8):714
    Raivola J; Dini A; Karvonen H; Piki E; Salokas K; Niininen W; Kaleva L; Zhang K; Arjama M; Gudoityte G; Seashore-Ludlow B; Varjosalo M; Kallioniemi O; Hautaniemi S; Murumagi A; Ungureanu D
  • Article: CELL REPORTS: METHODS. 2022;2(7):100256
    Sandstroem N; Carannante V; Olofsson K; Sandoz PA; Moussaud-Lamodiere EL; Seashore-Ludlow B; Van Ooijen H; Verron Q; Frisk T; Takai M; Wiklund M; Ostling P; Onfelt B
  • Article: CANCER RESEARCH. 2021;81(22):5733-5744
    Sanjiv K; Calderon-Montano JM; Pham TM; Erkers T; Tsuber V; Almlof I; Hoglund A; Heshmati Y; Seashore-Ludlow B; Danda AN; Gad H; Wiita E; Gokturk C; Rasti A; Friedrich S; Centio A; Estruch M; Vatsveen TK; Struyf N; Visnes T; Scobie M; Koolmeister T; Henriksson M; Wallner O; Sandvall T; Lehmann S; Theilgaard-Monch K; Garnett MJ; Ostling P; Walfridsson J; Helleday T; Berglund UW
  • Article: CANCERS. 2021;13(14):3604
    Ninou AH; Lehto J; Chioureas D; Stigsdotter H; Schelzig K; Akerlund E; Gudoityte G; Joneborg U; Carlson J; Jonkers J; Seashore-Ludlow B; Gustafsson NMS
  • Article: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(5):580-588
    Mou T; Pawitan Y; Stahl M; Vesterlund M; Deng W; Jafari R; Bohlin A; Osterroos A; Siavelis L; Backvall H; Erkers T; Kiviluoto S; Seashore-Ludlow B; Ostling P; Orre LM; Kallioniemi O; Lehmann S; Lehtio J; Trung NV
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Alla övriga publikationer

  • Review: NATURE REVIEWS DRUG DISCOVERY. 2025;:1-22
    Tanoli Z; Fernandez-Torras A; Ozcan UO; Kushnir A; Nader KM; Gadiya Y; Fiorenza L; Ianevski A; Vaha-Koskela M; Miihkinen M; Seemab U; Leinonen H; Seashore-Ludlow B; Tampere M; Kalman A; Ballante F; Benfenati E; Saunders G; Potdar S; Garcia IG; Garcia-Serna R; Talarico C; Beccari AR; Schaal W; Polo A; Costantini S; Cabri E; Jacobs M; Saarela J; Budillon A; Spjuth O; Ostling P; Xhaard H; Quintana J; Mestres J; Gribbon P; Ussi AE; Lo DC; de Kort M; Wennerberg K; Fratelli M; Carreras-Puigvert J; Aittokallio T
  • Review: MED. 2024;5(11):1351-1377
    Tong L; Cui W; Zhang B; Fonseca P; Zhao Q; Zhang P; Xu B; Zhang Q; Li Z; Seashore-Ludlow B; Yang Y; Si L; Lundqvist A
  • Review: INTERNATIONAL IMMUNOPHARMACOLOGY. 2020;83:106446
    Hashemi V; Farhadi S; Chaleshtari MG; Seashore-Ludlow B; Masjedi A; Hojjat-Farsangi M; Namdar A; Ajjoolabady A; Mohammadi H; Ghalamfarsa G; Jadidi-Niaragh F

´¡²Ô²õ³Ùä±ô±ô²Ô¾±²Ô²µ²¹°ù

  • Senior Forskningsspecialist, Onkologi-Patologi, ̽»¨¾«Ñ¡, 2022-

Examina och utbildning

  • Docent, Experimentell onkologi, ̽»¨¾«Ñ¡, 2024

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