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Epidemiologi och patofysiologi vid allvarligt trauma och sepsis – Anders Oldners forskargrupp

Trauma och sepsis är vanliga orsaker till intensivvårdsinläggning. Dessa tillstånd är nära sammanlänkade och medför hög dödlighet. Vi genomför translationella studier som sträcker sig från epidemiologi till in vitro-experiment inom detta område.

Our Research

Trauma is leading cause of death for individuals under the age of 45. We are conducting epidemiological studies on various aspects of trauma including risk factors, outcomes and long-term consequences of this devastating disease. Our group is also studying the serious complications encountered in intensive care of trauma victims such as multiple organ failure and sepsis. These studies also include dynamics of biomarkers induced by severe trauma and sepsis. 

Sepsis is causes more than 5 million deaths annually and remains a major challenge to the ̽»¨¾«Ñ¡ profession. We are conducting epidemiological studies on risk factors, magnitudes and outcomes of this lethal condition. We are also performing experimental studies on pathophysiological aspects mainly regarding endothelial dysfunction, a major component in the development of septic shock.

Publikationer

Utvalda publikationer

  • Article: JOURNAL OF CRITICAL CARE. 2019;54:125-129
    Eriksson J; Eriksson M; Brattstrom O; Hellgren E; Friman O; Gidlof A; Larsson E; Oldner A
  • Article: SCIENTIFIC REPORTS. 2019;9(1):58
    von Oelreich E; Eriksson M; Brattstrom O; Discacciati A; Strommer L; Oldner A; Larsson E
  • Article: BJS OPEN. 2018;2(6):392-399
    Eriksson M; von Oelreich E; Brattstrom O; Eriksson J; Latsson E; Oldner A
  • Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2018;62(7):962-973
    Halldorsdottir HD; Eriksson J; Persson BP; Herwald H; Lindbom L; Weitzberg E; Oldner A
  • Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2017;25(1):100
    von Oelreich E; Eriksson M; Brattstrom O; Discacciati A; Strommer L; Oldner A; Larsson E
  • Article: FREE RADICAL BIOLOGY AND MEDICINE. 2017;104:138-143
    Eriksson J; Gidlof A; Eriksson M; Larsson E; Brattstrom O; Oldner A
  • Article: BRITISH JOURNAL OF SURGERY. 2016;103(10):1282-1289
    Eriksson M; Brattstrom O; Larsson E; Oldner A
  • Article: JOURNAL OF TRAUMA AND ACUTE CARE SURGERY. 2015;79(3):407-412
    Eriksson M; Brattstrom O; Martensson J; Larsson E; Oldner A
  • Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2015;30(2):151-157
    Brattstrom O; Eriksson M; Larsson E; Oldner A
  • Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2014;58(5):549-559
    Persson BP; Halldorsdottir H; Lindbom L; Rossi P; Herwald H; Weitzberg E; Oldner A
  • Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2014;22:18
    Ghorbani P; Falken M; Riddez L; Sundelof M; Oldner A; Strommer L
  • Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2013;57(7):848-854
    Hyllienmark P; Brattstrom O; Larsson E; Martling C-R; Petersson J; Oldner A
  • Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2013;57(5):580-586
    Johansson J; Brattstrom O; Sjoberg F; Lindbom L; Herwald H; Weitzberg E; Oldner A
  • Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2012;27(3):233-241
    Brattstrom O; Larsson E; Granath F; Riddez L; Bell M; Oldner A
  • Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2012;27(2):576-581
    Martensson J; Martling C-R; Oldner A; Bell M
  • Article: BRITISH JOURNAL OF ANAESTHESIA. 2012;108(2):254-261
    Andersson A; Rundgren M; Kalman S; Rooyackers O; Brattstrom O; Oldner A; Eriksson S; Frithiof R
  • Article: JOURNAL OF VASCULAR RESEARCH. 2011;48(3):206-218
    Persson BP; Boels PJM; Lovdahl C; Rossi P; Arner A; Oldner A
  • Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2010;54(8):1007-1017
    Brattstrom O; Granath F; Rossi P; Oldner A
  • Article: INTENSIVE CARE MEDICINE. 2010;36(8):1333-1340
    Martensson J; Bell M; Oldner A; Xu S; Venge P; Martling C-R
  • Article: SHOCK. 2009;32(4):427-434
    Persson BP; Rossi P; Weitzberg E; Oldner A
  • Article: ACTA PHYSIOLOGICA. 2009;196(4):375-383
    A'roch R; Steendijk P; Oldner A; Weitzberg E; Konrad D; Johansson G; Haney M
  • Article: INTENSIVE CARE MEDICINE. 2008;34(5):873-880
    Rossi P; Persson B; Boels PJM; Arner A; Weitzberg E; Oldner A
  • Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2007;293(2):H988-H996
    Konrad D; Haney M; Johansson G; Wanecek M; Weitzberg E; Oldner A
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Finansiering

  • European Society of Intensive Care Medicine
  • Stockholm County Council
  • Carnegie Foundation
  • Magnus Bergvall Foundation
  • Laerdal Foundation
  • Swedish Society of Medicine
  • Swedish Cancer and Traffic Injury Society Fund 
  • LPS Medical Foundation

Medarbetare och kontakt

Gruppledare

Alla medarbetare i gruppen

Former group members:

  • Patrik Rossi, MD, PhD, former doctoral student
  • David Konrad, MD, PhD, former doctoral student
  • Michael Wanecek, MD, PhD, former doctoral student and co-supervisor
  • Olof Brattström â€“ MD PhD, co-supervisor
  • Björn P. Persson â€“ MD PhD, co-supervisor
Nyckelord:
Anestesi och intensivvård
AO
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2024-03-22